Evolutionary developmental biology (evo-devo) has undergone dramatic transformations since its emergence as a distinct discipline. This paper aims to highlight the scope, power, and future promise of evo-devo to transform and unify diverse aspects of biology. We articulate key questions at the core of eleven biological disciplines—from Evolution, Development, Paleontology, and Neurobiology to Cellular and Molecular Biology, Quantitative Genetics, Human Diseases, Ecology, Agriculture and Science Education, and lastly, Evolutionary Developmental Biology itself—and discuss why evo-devo is uniquely situated to substantially improve (...) our ability to find meaningful answers to these fundamental questions. We posit that the tools, concepts, and ways of thinking developed by evo-devo have profound potential to advance, integrate, and unify biological sciences as well as inform policy decisions and illuminate science education. We look to the next generation of evolutionary developmental biologists to help shape this process as we confront the scientific challenges of the 21st century. (shrink)

Toward the end of his life, the Russian psychologist L.S. Vygotsky turned away from his earlier work that he has become famous for only to sow the seeds for a new theory. In this theory, affect was to play a central role, there was to be a primacy of social relations, and anything mental (mind, thought, self, other, knowledge) was an event rather than a thing. This is essentially a transactional perspective. In this book, the author articulates a transactional psychology (...) of education drawing on the works of G.H. Mead, J. Dewey, G. Bateson, F. Mikhailov, and E. Il'enkov. All theoretical positions are developed out of videotaped exchanges, thereby giving concrete character to every psychological concept articulated. (shrink)

This book compares Chinese thought to that of the West. With recent Western interest in Chinese Buddhism (also known as Zen) and Daoism an understanding of their underlying ways of thinking is crucial for approaching them properly. The topics treated include worldview, world -- man relation, and mind and consciousness. A unique feature of the book is the comparison between Daoism and Chinese Buddhism on the one hand, and the Greek schools of Epicureanism and Stoicism on the other. A remarkable (...) similarity as well as a significant difference is found between these ways of life. In both China and Greece they learned how to live in the 'Now'. But in China this is centred around the body, while in Greece this was a strictly rational pursuit. The main differences between the Chinese and Western ways can be summarised in the words 'accord' and 'separation'. Clearly, in East and West different roads have been, and still are walked. Yet, these roads do not inevitably entail different ways of life. 'Walking two roads at once' (Zhuangzi) it is possible to go beyond accord and separation. (shrink)

This work combines two early pamphlets by F. H. Bradley , the foremost philosopher of the British Idealist movement. The first essay, published in 1874, deals with the nature of professional history, and foreshadows some of Bradley's later ideas in metaphysics. He argues that history cannot be subjected to scientific scrutiny because it is not directly available to the senses, meaning that all history writing is inevitably subjective. Though not widely discussed at the time of publication, the pamphlet was influential (...) on historian and philosopher R. G. Collingwood. The second pamphlet is Bradley's critique of Henry Sidgwick's The Methods of Ethics. Sidgwick was the first to propose the paradox of hedonism, which is the idea in ethics that pleasure can only be acquired indirectly. Published in 1877, this work is divided into three parts, treating Sidgwick's definitions, arguments, and his view of ethical science. (shrink)

"Not only one of the best but also the most comprehensive treatment of Stoicism written in this century." --Times Literary Supplement.

Sugar, pork, beer, corn, cider, scrapple, and hoppin' John all became staples in the diet of colonial America. The ways Americans cultivated and prepared food and the values they attributed to it played an important role in shaping the identity of the newborn nation. In A Revolution in Eating, James E. McWilliams presents a colorful and spirited tour of culinary attitudes, tastes, and techniques throughout colonial America. Confronted by strange new animals, plants, and landscapes, settlers in the colonies and West (...) Indies found new ways to produce food. Integrating their British and European tastes with the demands and bounty of the rugged American environment, early Americans developed a range of regional cuisines. From the kitchen tables of typical Puritan families to Iroquois longhouses in the backcountry and slave kitchens on southern plantations, McWilliams portrays the grand variety and inventiveness that characterized colonial cuisine. As colonial America grew, so did its palate, as interactions among European settlers, Native Americans, and African slaves created new dishes and attitudes about food. McWilliams considers how Indian corn, once thought by the colonists as "fit for swine," became a fixture in the colonial diet. He also examines the ways in which African slaves influenced West Indian and American southern cuisine. While a mania for all things British was a unifying feature of eighteenth-century cuisine, the colonies discovered a national beverage in domestically brewed beer, which came to symbolize solidarity and loyalty to the patriotic cause in the Revolutionary era. The beer and alcohol industry also instigated unprecedented trade among the colonies and further integrated colonial habits and tastes. Victory in the American Revolution initiated a "culinary declaration of independence," prompting the antimonarchical habits of simplicity, frugality, and frontier ruggedness to define American cuisine. McWilliams demonstrates that this was a shift not so much in new ingredients or cooking methods, as in the way Americans imbued food and cuisine with values that continue to shape American attitudes to this day. (shrink)

In describing the flawless regularity of developmental processes and the correlation between changes at certain genetic loci and changes in morphology, biologists frequently employ two metaphors: that genes ‘control’ development, and that genomes embody ‘programs’ for development. Although these metaphors have an admirable sharpness and punch, they lead, when taken literally, to highly distorted pictures of developmental processes. A more balanced, and useful, view of the role of genes in development is that they act as suppliers of the material needs (...) of development and, in some instances, as context‐dependent catalysts of cellular changes, rather than as ‘controllers’ of developmental progress and direction. The consequences of adopting this alternative view of development are discussed. (shrink)

Background Integrating artificial intelligence (AI) into healthcare has raised significant ethical concerns. In pharmacy practice, AI offers promising advances but also poses ethical challenges. Methods A cross-sectional study was conducted in countries from the Middle East and North Africa (MENA) region on 501 pharmacy professionals. A 12-item online questionnaire assessed ethical concerns related to the adoption of AI in pharmacy practice. Demographic factors associated with ethical concerns were analyzed via SPSS v.27 software using appropriate statistical tests. Results Participants expressed concerns (...) about patient data privacy (58.9%), cybersecurity threats (58.9%), potential job displacement (62.9%), and lack of legal regulation (67.0%). Tech-savviness and basic AI understanding were correlated with higher concern scores (p < 0.001). Ethical implications include the need for informed consent, beneficence, justice, and transparency in the use of AI. Conclusion The findings emphasize the importance of ethical guidelines, education, and patient autonomy in adopting AI. Collaboration, data privacy, and equitable access are crucial to the responsible use of AI in pharmacy practice. (shrink)

This work combines two early pamphlets by F. H. Bradley, the foremost philosopher of the British Idealist movement. The first essay, published in 1874, deals with the nature of professional history, and foreshadows some of Bradley's later ideas in metaphysics. He argues that history cannot be subjected to scientific scrutiny because it is not directly available to the senses, meaning that all history writing is inevitably subjective. Though not widely discussed at the time of publication, the pamphlet was influential on (...) historian and philosopher R. G. Collingwood. The second pamphlet is Bradley's critique of Henry Sidgwick's The Methods of Ethics. Sidgwick was the first to propose the paradox of hedonism, which is the idea in ethics that pleasure can only be acquired indirectly. Published in 1877, this work is divided into three parts, treating Sidgwick's definitions, arguments, and his view of ethical science. (shrink)

An anthology presenting dozens of provocative literary and historical writings drawn from 250 years of American history to increase cultural literacy.

Prior to the end of the Cold War, the word 'democracy' was rarely used by international lawyers. Few international organisations supported democratic governance, and the criteria for recognition of governments took little account of whether regimes enjoyed a popular mandate. But the events of 1989–1991 profoundly shook old assumptions. Democratic Governance and International Law attempts to assess international law's new-found interest in fostering transitions to democracy. Is an entitlement to democratic government now emerging in international law? If so, what are (...) its normative foundations? How have global and regional organisations encouraged transitions to democracy, and are their efforts consistent with their constitutional frameworks? How should international law react to elections in which profoundly anti-democratic parties win the vote? In this volume, leading legal scholars grapple with these and other questions to assess the future of international law on this most domestic of questions. (shrink)